MPhil Project: Surface Modification of Titanium Alloys for Biomedical Applications

Technological University Dublin


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  • Dublin, Ireland
    Technological University Dublin
    Feb 21, 2020

Supervisor name & contact details:

Susan Warren

School of Chemical & Pharmaceutical Sciences

[email protected]

Research Centre Name and Website

https://www.crestdit.com/

Please indicate if the intention is to transfer from the Masters programme to the PhD programme (subject to funding being available)

Yes x

No

   

Funding Agency

TU Dublin

Funding Details

Student Stipend                  € 16,000 p.a. for 2 years

Materials/ Travel etc         € 2,000 p.a. for 2 years

Fees                                      € p.a. for 2 years

Subject Area

New Materials & Devices

Title of the Project

MPhil Project: Surface Modification of Titanium Alloys for Biomedical Applications

Project Description

There are various approaches for surface modification of titanium orthopaedic implants to facilitate osseointegration and to mitigate possible adverse tissue responses, such as foreign body reaction and implant infection. The most common surface modification that has been shown to improve osseointegration of implants is the use of hydroxyapatite (HA) coatings. However, there are questions related to the robustness of HA coatings and their ability to withstand physiological loads (e.g. growth factors, bioactive molecules) without fragmentation.

An alternative approach that is being investigated by CREST researchers is to treat the metal surface by anodising. This process involves electrochemically oxidising the titanium substrate so as to grow an oxide layer on the surface. This oxide layer can provide an increased surface area with anchor sites for adhesion of coatings and/or inclusion of target leachates. The CREST group have developed extensive experience with anodising on both aluminium and titanium substrates over the past number of years.

This project will aim to:

a) develop a porous titanium anodic layer that

b) will include osteogenesis promoters, such as magnesium ions, and

c) will be capable of leaching at a controlled rate.

 

Project Aim

Enhance the performance of a stable titanium anodic surface by incorporating magnesium to aid the bone-implant integration.

Objectives

1.       To develop a non-HF electrolyte and process for preparing nanostructured anodic surfaces.

2.       To develop methodologies to incorporate magnesium into the titanium oxide layer

3.       To tune the anodic layer to aid controlled release of magnesium.

4.       To compare the effect of surface oxide layers between devices produced by 3D printing and conventional manufacturing processes.

 

Student requirements for this project
min. 2.1 BSc in Chemical Sciences

Or

2.2 BSc in Chemical Sciences with relevant industry experience

   

If you are interested in submitting an application for this project, please complete an Expression of Interest and email it to [email protected]