Postdoctoral fellow in Plant Transcriptomics and Pathway Elucidation

Université de Tours


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  • EA2106 BBV - Faculty of Pharmacy, 31 avenue Monge, 37200 Tours - France
    Université François Rabelais de Tours
    Oct 1, 2020

A three-year fellowship is available at the Department of Plant Biomolecules and Biotechnology (EA2106 BBV), University of Tours, France, from January 2021. This fellowship is open to Post-Doctoral researchers and for this project, you will work under the supervision of Dr. Vincent Courdavault (https://twitter.com/v_courdavault).   

The proposed Project

The recruited candidate will be involved in an exciting research program funded by French Agence Nationale de la Recherche (ANR–MIACYC project) associating BBV and the BioCIS lab (https://www.biocis.universite-paris-saclay.fr/) from the Paris-Saclay University. MIACYC focuses on the elucidation of biosynthetic pathways of highly valuable monoterpene indole alkaloids (MIA), with a particular emphasize on atypical reactions of MIA cyclisation. The candidate will carried out RNA-sequencing and single-cell RNA seq of selected MIA-producing plants. By conducting an extensive analysis of these newly developed datasets (gene coexpression networks…), the recruited researcher will predict candidate genes potentially catalyzing this expected cyclisation reactions. These genes will be further validated by functional genomic and biochemical approaches performed in close collaboration with other researchers from this project. The recruited researcher will also benefit from the expertise of several assistant professors and other post-docs from EA2106 with recognized skills/experience in the study of the NP biosynthesis/transcriptomics/metabolic engineering.

The BBV Laboratory

The BBV laboratory (EA2106) from the University of Tours studies plant specialized metabolisms by combining both metabolomics and transcriptomics approaches. Besides unraveling biosynthetic pathways, our goal is to provide alternative supply of plant natural products by creating microbiological cell factories. Our english-speaking lab offers all facilities (computing grids, LC-MS/MS, greenhouses, confocal microscope) to achieve and efficient research and benefits from funds from the European H2020 program, the French Agence Nationale de la Recherche (ANR) and from regional research programs. Please visit us at: (https://twitter.com/BBVEA2106_Tours)   (https://www.facebook.com/BBVEA2106/).

What we offer

We offer a three-year fellowship opening in January 2021. The eligible fellow will be granted social security benefits and will be paid 27 000-28 000€ (net wage) per year.

 

The expected profile

  • PhD in plant molecular biology, plant bioinformatics or plant biotechnology
  • Hands-on experience in bioinformatics, RNA sequencing, scRNA sequencing, gene expression networking or other NGS workflows is mandatory.
  • General skills in molecular biology
  • Spirit team and will of taking initiatives
  • Proficient use of the English language for both oral and written communication

 

How to apply

To apply, please send your detailed CV (including list of publications), motivation letter and appreciation letters from two referees at [email protected].  Applications are welcome from now and until the position is filled.